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Product name?Kojic Acid?Appearance?White crystal powder
CAS No?501-30-4?Purity?99.0% min
EINECS No.?207-922-4?Grade?Pharmaceutical and food
Molecular formula?C6H6O4?Molecular weight?142.1
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Description?
Diosmin is a naturally occurring flavonoid glycoside that can be isolated from various plant sources or derived from the flavonoid hesperidin. Diosmin was first isolated in 1925 from Scrophularia nodosa, and first introduced as a therapeutic agent in 1969. Diosmin is a biogenic amine derived by extracting hesperidin from Citrus Aurantium L., followed by conversion of hesperidin to diosmin. Diosmin is considered to be a vascular-protecting agent used to treat chronic venous insufficiency, hemorrhoids, lymphedema, and varicose veins. As a flavonoid, diosmin also exhibits anti-inflammatory, free-radical scavenging, and antimutagenic properties. Diosmin has been used for more than 30 years as a phlebotonic and vascularprotecting agent, and has recently begun to be investigated for other therapeutic purposes, including cancer, premenstrual syndrome, colitis, and diabetes.
Main Function?
(1) Daily chemicals material:Because kojic acid can inhibits caseinase activity,then inhibits skin melanin formation,Kojic acid and it,s derivatives widely used in high-quality skin lightening cosmetics, bath preparation and mouth or teeth care products. Cosmetics containing kojic acid can treat freckle,acne, pigmentation and macula effectively without any toxic and side effects. At present, kojic acid,s level added in comestics is from 0.2 to 1.0 percent.
(2) Medicine material: Kojic acid and it,s derivatives are used as an important material in antibiotic -cephamycin,anodyne, and antiphlogistic production.
(3) Food additive:Koj ic acid and it,s derivatives work as antiseptic,antioxidant, preservative and color stablizer in meat processing, also act as useful materials of food aromatizer - maltol and ethylmaltol.
(4) Preservative and color stablizer of cut-flower: Kojic acid and it,s derivatives are added to cut-flower to keepflower colorful and fresh.
(5) Kojic acid has been used as film despecking agent and iron ananysis reagent.
(6) Kojic acid also is non-toxic to person and livestock, pollution-free pesticide in insecticide.
Application?Because kojic acid and its ramification can inhibit safest the melanin growing of body-skin, its application is being more and more wide in whiten cosmetic, bath lotion, toothpaste etc. As to its actions of antiseptic,antioxidant and color-care, kojic acid also can be widely used in food aseptic,antioxidant of grease and food,antistaling agent of fruit and vegetable,and color-care antistaling agent of meat products and marine products. In addition, kojic acid can also be used in antibiotic synthetic intermediate products, agriculture plant tutelage and chemical reagent, etc .
Shelf life?2 years?Supplier Name?Xi'an Rongsheng Biotechnology Co., Ltd.
Package?1kg/foil bag(net weight 1kg, gross weight 1.2kg), 25kg/fiber drum(net weight 25kg, gross weight 28kg)
Storage?Stored in a cool and dry well closed container and in ventilated area,
Kept away from moisture and strong light or high temperature.
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Kojic Acid??
Scientific name 5-hydroxy-2-hydroxamethy-1,4-pyrone.
1.?A weak-acid of organic compound which fermented by a kind of microorganism.,called Kojic acid.
2.?Kojic acid is white or cream colored acicular crytal, dissolving water, alcohol, acetone, slightly dissolving ether second ester of second acid, chloroform and pyridine, non-dissolving benzene.
Item?Specification?Result
Assay?99%?99.5%
Appearance?White or off white crystal?conforms
Odor?Characteristic?conforms
Taste?Characteristic?conforms
Particle Size?NLT 100% Through 80 mesh?conforms
Loss on Drying?<2.0%?0.47%
Heavy metals
Total Heavy Metals?≤10ppm?conforms
Arsenic?≤3ppm?conforms
Lead?≤3ppm?conforms
Microbiological Tests
Total Plate Count?≤1000cfu/g?conforms
Total Yeast & Mold?≤100cfu/g?conforms
E.Coli?Negative?Negative
Salmonella?Negative?Negative
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?1kg with double plastic container inside/Aluminum foil bag outside.
25kg with double plastic container inside/Fiber drum outside or to be discussed
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Biddle Sawyer Fortune Chem ( Asian Sales Division of Biddle Sawyer New York ) sells proven
quality Kojic Acid on a regular basis.
Contact Point :
Mr.? S. M. Kang, CEO
Mr.? Jingu Kang, Manager
Tel : 82-(0)51-701-9121
Fax : 82-(0)51-701-9125
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Please click “ CONTACT SUPPLIER “ above so that we may reply therein or inform you the person in charge name and his/her email address and company website.?
All Payment including shipping documents procedure and strict quality management to be done by Biddle Sawyer New York in cooperation with very well-trained ( including TBM : Time Based Management ) Biddle Sawyer’s overseas offices and affiliations
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Custom Manufacturing and Development Capabilities
R&D at 6 labs (affiliate or contract)
~350 Chemists at 6 facilities in USA, China, Korea, Taiwan, India and Finland
~40 PhD's, ~120 M.S.; External consultants welcomed
~400 combined hoods
Up to 100L vessels in labs
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Development Services
Tech Transfer
Process R&D
Analytical Development
Custom Synthesis; FTE
Kilo lab production
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Analytical Equipment
LC's GC's LC/MS GC/MS NMR IR UV KF
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Production Capabilities
Production at 6 plants (affiliate or contract)
>150 vessels at 6 facilities in USA, China, Korea, Taiwan and Finland
>2000m3 capacity
Vessels from 300L to 10,000L
Temps from -80 to 350C
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Production Services
Tech Transfer
Scale Up
Optimization
Non-GMP and GMP (FDA inspected)
Pilot to large commercial scale
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